Meet
Adalimumab-bwwd
An FDA-approved biosimilar
to HUMIRA® (adalimumab) A biosimilar is a medicine made to be very close to another approved biologic medicine. It works the same way in the body and is just as safe and effective as the original medicine it is based on (called the reference product).

Actor
Portrayal

What is
Adalimumab-bwwd?

FDA-approved for many of the same medical conditions as HUMIRA.

  • In adults:
  • Moderate to severe rheumatoid arthritis (RA)
  • Psoriatic arthritis (PsA)
  • Ankylosing spondylitis (AS)
  • Moderate to severe hidradenitis suppurativa (HS)
  • Moderate to severe chronic plaque psoriasis (Ps)
  • Moderate to severe ulcerative colitis (UC)
  • Non-infectious intermediate, posterior, and panuveitis
  • In adults and pediatric patients 6 years of age and older:
  • Moderate to severe Crohn’s disease (CD)
  • In patients 2 years of age and older:
  • Moderate to severe polyarticular juvenile idiopathic arthritis (JIA)

Studied and proven to share the same safety profile as HUMIRA; Adalimumab-bwwd is associated with serious infections (sometimes fatal) as well as certain forms of cancer in children and adults. Please see the full prescribing information including BOXED WARNING and talk with your doctor if you have questions.

If you switch from HUMIRA to Adalimumab-bwwd, there are no differences in the Medication Guides regarding instructions for use or storage.

How to take Adalimumab-bwwd

Notice: Adalimumab-bwwd is available only in autoinjector and prefilled syringe in the USA. Treatment eligibility is limited for some patients.

For questions about injections, please consult your health care provider and read the full Prescribing Information, including BOXED WARNING, Medication Guide, and Instructions for Use.

Autoinjector Training

See the Adalimumab-bwwd autoinjector full Instructions for Use.

Prefilled Syringe Training

See the Adalimumab-bwwd prefilled syringe full Instructions for Use.

Actor
Portrayal

Adalimumab-bwwd
Co-Pay Program

If you’re eligible, you could pay as little as $0 for Adalimumab-bwwd

  • If you qualify, you can start using your co-pay card right away
  • Your card doesn’t expire—you’ll be automatically re-enrolled every year

See if you're eligible

If you have any questions, or need injection support, please contact the Cordavis Help-Line at 1-833-267-3070.

Indications & Important Safety Information

What is Adalimumab-bwwd?

Adalimumab-bwwd is a prescription medicine used:

  • To reduce the signs and symptoms of:
    • Moderate to severe rheumatoid arthritis (RA) in adults. Adalimumab-bwwd can be used alone, with methotrexate, or with certain other medicines.
    • Moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years and older. Adalimumab-bwwd can be used alone, or with methotrexate.
    • Psoriatic arthritis (PsA) in adults. Adalimumab-bwwd can be used alone or with certain other medicines.
    • Ankylosing spondylitis (AS) in adults.
    • Moderate to severe hidradenitis suppurativa (HS) in adults.
  • To treat moderate to severe Crohn’s disease (CD) in adults and children 6 years of age and older.
  • To treat moderate to severe ulcerative colitis (UC) in adults. Limitations of Use: The effectiveness of adalimumab products has not been established in patients who have lost response to or were intolerant to TNF blockers.
  • To treat moderate to severe chronic (lasting a long time) plaque psoriasis (Ps) in adults who have the condition in many areas of their body and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).
  • To treat non-infectious intermediate (middle part of the eye), posterior (back of the eye), and panuveitis (all parts of the eye) in adults.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about Adalimumab-bwwd?

You should discuss the potential benefits and risks of Adalimumab-bwwd with your doctor. Adalimumab-bwwd is a tumor necrosis factor (TNF) blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking Adalimumab-bwwd if you have any kind of infection unless your doctor says it is okay.

Serious infections have happened in people taking adalimumab products. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting Adalimumab-bwwd, and check you closely for signs and symptoms of TB during treatment with Adalimumab-bwwd, even if your TB test was negative. If your doctor feels you are at risk for TB, you may be treated with medicine for TB before you begin treatment with Adalimumab-bwwd and during treatment with Adalimumab-bwwd.

Cancer. For children and adults taking TNF blockers, including Adalimumab-bwwd, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If you use TNF blockers, including Adalimumab-bwwd, your chance of getting 2 types of skin cancer (basal cell and squamous cell) may increase. These types of cancer are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that does not heal.

What should I tell my doctor BEFORE starting Adalimumab-bwwd?

Tell your doctor about all of your medical conditions, including if you:

  • Have an infection, are being treated for infection, or have symptoms of an infection.
  • Get a lot of infections or infections that keep coming back.
  • Have diabetes.
  • Have TB or have been in close contact with someone with TB, or were born in, lived in, or traveled where there is more risk for getting TB.
  • Live or have lived in certain parts of the country (such as the Ohio and Mississippi River valleys) where there is an increased risk for getting certain kinds of fungal infections (histoplasmosis, coccidioidomycosis, or blastomycosis). These infections may happen or become more severe if you use Adalimumab-bwwd. Ask your doctor if you do not know if you have lived in an area where these infections are common.
  • Have or have had hepatitis B.
  • Are scheduled for major surgery.
  • Have or have had cancer.
  • Have numbness or tingling or a nervous system disease, such as multiple sclerosis or Guillain-Barré syndrome.
  • Have or had heart failure.
  • Have recently received or are scheduled to receive a vaccine. Adalimumab-bwwd patients may receive vaccines, except for live vaccines. Children should be brought up to date on all vaccines before starting Adalimumab-bwwd.
  • Are allergic to Adalimumab-bwwd or any of its ingredients.
  • Are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.
  • Have a baby and were using Adalimumab-bwwd during your pregnancy. Tell your baby’s doctor before your baby receives any vaccines.

Also tell your doctor about all the medicines you take. You should not take Adalimumab-bwwd with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (6-mercaptopurine, 6-MP).

What should I watch for after starting Adalimumab-bwwd?

Adalimumab-bwwd can cause serious side effects, including:

  • Serious infections. These include TB and infections caused by viruses, fungi, or bacteria. Symptoms related to TB include a cough, low-grade fever, weight loss, or loss of body fat and muscle.
  • Hepatitis B infection in carriers of the virus. Symptoms include muscle aches, feeling very tired, dark urine, skin or eyes that look yellow, little or no appetite, vomiting, clay-colored bowel movements, fever, chills, stomach discomfort, and skin rash.
  • Allergic reactions. Symptoms of a serious allergic reaction include hives, trouble breathing, and swelling of your face, eyes, lips, or mouth.
  • Nervous system problems. Signs and symptoms include numbness or tingling, problems with your vision, weakness in your arms or legs, and dizziness.
  • Blood problems (decreased blood cells that help fight infections or stop bleeding). Symptoms include a fever that does not go away, bruising or bleeding very easily, or looking very pale.
  • Heart failure (new or worsening). Symptoms include shortness of breath, swelling of your ankles or feet, and sudden weight gain.
  • Immune reactions including a lupus-like syndrome. Symptoms include chest discomfort or pain that does not go away, shortness of breath, joint pain, or rash on your cheeks or arms that gets worse in the sun.
  • Liver problems. Symptoms include feeling very tired, skin or eyes that look yellow, poor appetite or vomiting, and pain on the right side of your stomach (abdomen). These problems can lead to liver failure and death.
  • Psoriasis (new or worsening). Symptoms include red scaly patches or raised bumps that are filled with pus.

Call your doctor or get medical care right away if you develop any of the above symptoms.

Common side effects of Adalimumab-bwwd include injection site reactions (pain, redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, and rash. These are not all of the possible side effects with Adalimumab-bwwd. Tell your doctor if you have any side effect that bothers you or that does not go away.

Remember, tell your doctor right away if you have an infection or symptoms of an infection, including:

  • Fever, sweats, or chills
  • Muscle aches
  • Cough
  • Shortness of breath
  • Blood in phlegm
  • Warm, red, or painful skin or sores on your body
  • Diarrhea or stomach pain
  • Burning when you urinate
  • Urinating more often than normal
  • Feeling very tired
  • Weight loss

Adalimumab-bwwd is given by injection under the skin.

This is not all of the important information to know about Adalimumab-bwwd. For more information, talk to your health care provider.

Please read the accompanying Medication Guide for Adalimumab-bwwd, including the information about serious infections and cancers, and discuss it with your doctor. The Instructions for Use and Physician Prescribing Information are also available.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indications & Important Safety Information

What is Adalimumab-bwwd?

Adalimumab-bwwd is a prescription medicine used:

  • To reduce the signs and symptoms of:
    • Moderate to severe rheumatoid arthritis (RA) in adults. Adalimumab-bwwd can be used alone, with methotrexate, or with certain other medicines.
    • Moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years and older. Adalimumab-bwwd can be used alone, or with methotrexate.
    • Psoriatic arthritis (PsA) in adults. Adalimumab-bwwd can be used alone or with certain other medicines.
    • Ankylosing spondylitis (AS) in adults.
    • Moderate to severe hidradenitis suppurativa (HS) in adults.
  • To treat moderate to severe Crohn’s disease (CD) in adults and children 6 years of age and older.
  • To treat moderate to severe ulcerative colitis (UC) in adults. Limitations of Use: The effectiveness of adalimumab products has not been established in patients who have lost response to or were intolerant to TNF blockers.
  • To treat moderate to severe chronic (lasting a long time) plaque psoriasis (Ps) in adults who have the condition in many areas of their body and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).
  • To treat non-infectious intermediate (middle part of the eye), posterior (back of the eye), and panuveitis (all parts of the eye) in adults.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about Adalimumab-bwwd?

You should discuss the potential benefits and risks of Adalimumab-bwwd with your doctor. Adalimumab-bwwd is a tumor necrosis factor (TNF) blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking Adalimumab-bwwd if you have any kind of infection unless your doctor says it is okay.

Serious infections have happened in people taking adalimumab products. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting Adalimumab-bwwd, and check you closely for signs and symptoms of TB during treatment with Adalimumab-bwwd, even if your TB test was negative. If your doctor feels you are at risk for TB, you may be treated with medicine for TB before you begin treatment with Adalimumab-bwwd and during treatment with Adalimumab-bwwd.

Cancer. For children and adults taking TNF blockers, including Adalimumab-bwwd, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If you use TNF blockers, including Adalimumab-bwwd, your chance of getting 2 types of skin cancer (basal cell and squamous cell) may increase. These types of cancer are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that does not heal.